RATULS

Overall no direct effect of robot-assisted training, but ‘clinically important’ improvements in daily function.

ASTER 2

Combined methods were no better than the standard approach to pulling out blood clots in acute stroke

PASTA

No increase in the rate or speed of thrombolysis, but may represent better-informed treatment decisions with subsequently reduced care costs.

RESTART

Now clinicians can be reassured that antiplatelet
drugs are safe after brain bleeds.

RESCUE Brain

A neutral trial of remote ischaemic conditioning within 6 hours of stroke; however, ongoing trials will determine if the method is efficient in a different setting.

Microbleeds International Collaborative Network

In TIA/stroke patients with many asymptomatic small bleeds on a brain scan, the risk of bleeding does not outweigh
the risk of ischaemic stroke.

Meta-analysis of  EXTEND, ECASS4, and EPITHET

We are now confident that clot-busters are beneficial
up to 9 hours after stroke.

TAKING CHARGE AFTER STROKE

Statistically significant improvements in quality of life, independence and activities of daily living with this low-cost self-management approach.

INTERACT2 / ATACH-II IPD POOLING PROJECT

Outcomes in patients with a brain bleed
continue to improve as blood pressure
is lowered.

THAWS

Early termination precludes definitive conclusions about the effectiveness of lower dose thrombolysis in patients who wake up with stroke selected by mismatch.

TICH-2

Acute treatment with tranexamic acid acute in brain haemorrhage may improve survival at 1 year.

IMPACT – 24B